How many animals have been to space?

Hundreds. The first animals to make the trip were fruit flies launched in a V-2 rocket captured by the US in 1947. The exact number of flies was not recorded. The first mammals to survive a return trip to space were two Russian dogs, Gypsy and Dezik, in 1951. Since then monkeys, chimps, mice, rabbits, rats, frogs, guinea pigs, cats, wasps, beetles, tortoises, mealworms, fish, spiders, stick insects, newts, shrimp, crickets, snails, sea urchins, moths, jellyfish, silkworms, bees, ants, cockroaches and turtles have all been sent into space.